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Generic Name
Clobetasol propionate
Trade Name
Cloderm
Manufacturer
Eipico
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • topical carticosteroid used for severe resistant inflammatory skin disorders.
  • Fetal Risk
    Fetal Risk
  • Animal studies reported teratogenic effect of systemic corticosteroids especially cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft palate.
  • Limited human data but reported possible association with cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft palate, growth retardation, neonatal cataract and adrenal suppression in infants of mothers exposed during pregnancy to systemic corticosteroid therapy.
  • systemic use of corticosteroid increases the incidence of pre-eclampsia (one study) and preterm PROM (premature rupture of membranes).
  • No data for topical corticosteroids.
  • Breast Feeding
    Breast Feeding
  • Low dose systemic corticosteroids (prednisolone less than 20 mg)is safe in breast feeding.
  • No data with topical use.
  • Excreted into milk.
  • Safe in breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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