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Generic Name
Multivitamin, mineral (29)
Trade Name
Centrum
Drug Image
Centrum
Risk Category
No Data <ul> <li>Risk classification not available</li> </ul>
FDA Pregnancy Risk Categories

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Indication
Indication
  • Composition: vitamin A (5.000 Iu), E (30 Iu) C(90), Folic acid, B1 (2.25 mg), B2, B6, B12, D biotin, pantothenic acid, magnesium, copper manganese, potassium, zinc, phosphorus, iodine, iron, calcium. Nicotinamide (20mg).
  • Fetal Risk
    Fetal Risk
  • The doses of Vit E, C, B1, B2, B6, B12, and nicotinamide are above the recommended dietary allowance (rda) in pregnancy.
  • No data for phosphorus, manganese, biotin in pregnancy.
  • No adequate human data but suggested possible association between high doses of :
  • Vitamin C and anencephaly, infantile convulsions: Aka Salaam attacaks. Rare form of epilepsy usually between 3 and 8 months of age. They are spasms or involuntary flexing of the whole upper body">infantile scurvy.
  • Vitamin B1 and anecephaly.
  • Vitamin B6 and phocomelia, infantile convulsions: Aka Salaam attacaks. Rare form of epilepsy usually between 3 and 8 months of age. They are spasms or involuntary flexing of the whole upper body">infantile convulsions.
  • No fetal harm has been reported from high doses of vitamin E and B12.
  • The dose of calcium is within the rda in pregnancy but should be avoided in the 1st trimester because of possible association with congenital anomalies. Safe in the second and third trimesters if chronic high doses are avoided that may cause fetal hypomagnesemia, increased deep tendon reflexes and increased muscle tone.
  • Iodine dose is within the rda in pregnancy but even pharmacologic doses may cause goiter in the fetus.
  • Magnesium should be avoided in first trimester, safe in second and third trimester if chronic high doses are avoided that can cause neonatal hypermagnesemia, drowsiness, decreased muscle tone, respiratory distress and cardiovascular impairment.
  • Potassium is safe in pregnancy but should be avoided in patients with renal impairment and cardiovascular disease.
  • The dose of zinc is within the rda in pregnancy.
  • Breast Feeding
    Breast Feeding
  • All vitamins are excreted into milk, safe if supplementation is needed.
  • With iodine use, infant’s thyroid function should be monitored.
  • No data about phosphorus, copper manganese, biotin.
  • Other Trade Names
     
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